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Melatonin(CAS No.73-31-4 )

Melatonin(CAS No.73-31-4 )

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Name:  Melatonin

Synonyms:  N-(2-(5-methoxyindol-3-yl)ethyl)acetamide; N-Acetyl-5-methoxytryptamine; 3-(N-Acetyl-2-aminoethyl)-5-methoxyindole 

Molecular Formula:  C13H16N2O2

Molecular Weight:  232.28

CAS Number:  73-31-4

EINECS:  200-797-7

 

Melatonin is a direct scavenger of OH, O2, and NO. Unlike other antioxidants, melatonin does not undergo redox cycling, the ability of a molecule to undergo reduction and oxidation repeatedly. Redox cycling may allow other antioxidants (such as vitamin C) to regain their antioxidant properties. Melatonin, on the other hand, once oxidized, cannot be reduced to its former state because it forms several stable end-products upon reacting with free radicals. Therefore, it has been referred to as a terminal (or suicidal) antioxidant

Melatonin has been studied for the treatment of cancer, immune disorders, cardiovascular diseases, depression, seasonal affective disorder (SAD), circadian rhythm sleep disorders and sexual dysfunction. Basic research indicates that melatonin may play a significant role in modulating the effects of drugs of abuse such as cocaine. The use of melatonin as a drug can entrain (synchronize) the circadian clock to environmental cycles and can have beneficial effects for treatment of certain forms of insomnia. Its therapeutic potential may be limited by its short biological half-life, poor bioavailability, and the fact that it has numerous non-specific actions. In recent studies though, prolonged release melatonin has shown good results in treating insomnia in older adults.

The primary motivation for the use of melatonin as a supplement may be as a natural aid to better sleep. Incidental benefits to health and well-being may accumulate, due to melatonin's role as an antioxidant and its stimulation of the immune system and several components of the endocrine system.

 

Specification

Test Items

Specifications

Product name

Melatonin

Appearance

White or pale-white crystalline powder

Identification

Accord with the test

Solubility

Soluble in alcohol, slightly soluble in water

Assay (HPLC)

99.0% Min

Loss on drying

0.5% Max

Residue on ignition

0.1% Max

Melting point

117-120ÂșC

Heavy metals (as Pb)

10ppm Max

 

Package:  25Kgs/Drum

Storage:   Stored in a dry and cool place, keep away from strong light and heat.

Shelf life:  Two years when stored properly in a well-closed container.