A dietary supplement containing an extract powder derived from the root of the ashwagandha shrub with potential antineoplastic, antioxidant, immunostimulating and anti-angiogenic activities. Ashwagandha root powder extract contains numerous alkaloids, including withanine as the primary alkaloid, and steroidal lactone withanolides. The withanolides in this agent may suppress nuclear factor-kappaB activation and nuclear factor-kappaB-regulated gene expression, potentiating apoptosis and inhibiting tumor cell invasion. Cultivated in India and North America, ashwagandha (Withania somnifera Dunal or Indian ginseng) belongs to the Solanaceae (nightshade) family. Ashwagandha can be used by both men and women and it acts to calm the mind and promote sound, restful sleep. Ashwagandha works as an adaptogen, promoting the body's ability to maintain homeostasis and resist stress. Ashwagandha prevents or minimizes imbalances that may lead to disease, whether from poor diet, lack of sleep, mental or physical strain, or chemical toxins in the environment. Ashwagandha is especially beneficial in stress related disorders such as arthritis, hypertension, diabetes, general debility, etc. It has also shown impressive results when used as a stimulant for the immune system. Ashwagandha is a unique herb with anti-stress adaptogenic action that leads to better physical fitness and helps to cope with life's daily stress.